Both clubs are considered European royalty, with Liverpool having won the famous trophy six times and Real Madrid a record 14 times.
Jurgen Klopp’s team have endured a difficult campaign this term but victories in their last two Premier League games have restored some confidence just at the right moment.
Their Spanish visitors are currently five points behind Barcelona in La Liga, and are fresh from recently being crowned Word Champions at the Club World Cup.
Here is everything you need to know ahead of this evening’s game.
What time does Liverpool vs Real Madrid kick-off?
Liverpool vs Real Madrid will kick-off tonight (Tuesday, February 21) at 8pm.
The return leg will be held in Madrid on Wednesday, March 15.
How to watch on TV and live stream
The game will be shown live on BT Sport 1 and BT Sport Ultimate for viewers in the UK.
Coverage will get underway on both channels from 7pm.
BT Sport customers can also live stream Liverpool vs Real Madrid on the BT Sport app and website.
Those without subscription to BT Sport can watch the match by purchasing a monthly pass for £29.99, which provides access to all four sports channels via the app and web player.
How to listen on radio
Live radio commentary will take place BBC Radio 5 Live, with the build-up beginning from 7pm.
Real Madrid won the last meeting between the two sides – the Champions League final in Paris last May.
The deadlock was broken just before the hour mark when Vinicius Junior scored past compatriot Alisson to ensure the trophy returned to the Spanish capital.
The previous season, Madrid knocked Liverpool out in the quarter-finals courtesy of a 3-1 win on aggregate.
The two famous old clubs also met in the 2018 final, with Los Blancos once again emerging victorious following a dramatic 3-1 victory in Kyiv.
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